How do you read a COA?

A Certificate of Analysis (COA) describes the tests a laboratory has performed on a sample and the results obtained. A useful report links those findings to an identifiable sample. Always read the complete document alongside the details of the exact product variant offered.

Start with the correct sample

Controleer de productnaam, productvorm, vermelde sterkte en het batchnummer. Een rapportnummer identificeert het document; een monster-ID identificeert het ingezonden monster. Deze nummers hebben een andere functie dan het batchnummer op het etiket.

Bij Novogin kan de documentatie van een product en batch meerdere milligramvarianten dekken. De gemeten hoeveelheid in het rapport blijft een resultaat voor het geteste monster. Houd rapportdekking, monsterresultaten en de registratie van de fysieke uitvoering daarom apart.

Controleer de product- en batchkoppeling in de bibliotheek. Een rapport voor een ander product of een volgende batch geldt niet automatisch. Ontbreekt de koppeling met uw ontvangen etiket? Vraag deze eerst na. Lees ook hoe u een analyserapport aan de actuele batch koppelt.

Three separate measurements to read

Identity: which substance was tested?

Look for the reported substance identification and the corresponding test. The product name or a purity percentage alone does not replace identity testing. Check what the laboratory actually tested and what conclusion it recorded.

Purity: what does the analysis compare?

A chromatographic purity percentage describes the ratio of measured components within the method used. It is not automatically the percentage by mass of the entire contents of a vial. Water, salts and other components may fall outside that measurement.

Quantity: how much was measured?

A quantitative result, expressed in milligrams for example, answers a different question. Check whether the result is stated per vial, per sample or using another unit. Compare it with the nominal quantity on the label. High purity alone does not prove that this quantity is present.

This explanation of chromatographic purity and peptide content is consistent with the technical guidance from Sigma-Aldrich. Always refer to the relevant report for the exact meaning and measurement method.

Wilt u deze uitkomsten naast elkaar vergelijken? Lees de uitleg over identiteit, zuiverheid en gemeten inhoud.

Check the method and date

Check who issued the report, which tests were performed and which methods were used. Also review the receipt date, analysis date and any approval date: these are not necessarily the same. If acceptance limits are stated, check how the result compares with them.

The WHO model for certificates of analysis shows how sample details, methods, results and assessment criteria are recorded together. This model comes from pharmaceutical quality control; citing it does not imply WHO approval of Novogin or any product.

Bekijk voor de gebruikte analysetechnieken ook wat HPLC en LC-MS meten.

What does a COA not establish on its own?

Draw a conclusion about a property only when the report contains an appropriate test and result for it. A purity statement, for example, is not separate evidence of sterility, absence of endotoxins or suitability for human use.

The report describes the sample tested. Establishing whether that sample represents the supplied batch also requires a traceable link and information about sampling. At Novogin, a publicly available download does not automatically mean that the batch is currently in stock or has been approved for release following review.

How to use the Novogin batch library

1. Select the product and check the exact strength and product form.
2. Compare the batch number or sample ID with your documentation.
3. Open the original report and read the results and units.
4. Check the report status and any explanation of discrepancies.
5. Ask about any missing information, stating the product, variant and batch number.

Go to Certificates to view the available reports. If documentation is missing or a link is unclear, please contact us.

Would you like to view the product specifications alongside this explanation? Explore the research peptide range for professional research.

This knowledge base explains analytical documentation for laboratory research. It does not provide advice on dosing, administration or medical use.

Bronnen

• WHO — Model certificate of analysis, Technical Report Series 1010, Annex 4 (2018): voorbeeld voor het vastleggen van monstergegevens, methoden, resultaten en beoordelingscriteria. Het betreft farmaceutische kwaliteitscontrole en geen goedkeuring van Novogin.
• Sigma-Aldrich — Peptide Sample Amount Determination: onderscheid tussen chromatografische peptidezuiverheid en peptidegehalte.